This prequiz has 12 true/false questions. It's designed to give you an indication of where gaps in your knowledge might be. Feedback has been included in this quiz. Scoring is at the bottom of the page. To answer the following questions, select the best answer, then select Check answer.

 

Question 01

Rubella antibody testing of pregnant women is routine in NSW. The test used is an ELISA capture assay, measuring specific IgM antibody.
True
False
Check answer

Explanation

IgG to Rubella is measured routinely in antenatal clinics in NSW

Question 02

Up to 90% of babies born to mothers infected with Rubella during the first 10 weeks will develop Congenital Rubella Syndrome.

True
False
Check answer

Explanation

Congenital rubella syndrome occurs in up to 90 per cent of babies born to women who are infected with rubella during the first ten weeks of their pregnancy.
http://www.health.nsw.gov.au/Infectious/factsheets/Factsheets/rubella.pdf

Question 03

Rubella is spread by both direct contact and by droplets in the air.

True
False
Check answer

Explanation

Rubella is spread from an infected person by droplets from the nose or mouth or by direct contact. Rubella is easily spread to people who have not been vaccinated or previously infected.
http://www.health.nsw.gov.au/Infectious/factsheets/Factsheets/rubella.pdf

Question 04

The incubation period for Rubella is 1 week.
True
False
Check answer

Explanation

The incubation period is 2 to 3 weeks

Question 05

The Rubella vaccination is given at 2, 4 and 6 months.
True
False
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Explanation

The Rubella vaccination is given at 12 and 18 months.

Question 06

IgG to Rubella crosses the placenta by receptor mediated endocytosis.
True
False
Check answer

Explanation

Large molecules such as IgG and Insulin are too big to cross the placenta, but IgG, such as to Rubella, can cross the placenta through a process called receptor mediated endocytosis. Therefore, maternal immunity is transferred for up to 6 months.

Question 07

Interferons promote resistance to viral infections by stimulating lymphocyte proliferation.
True
False
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Explanation

Interferons inhibit viral replication and cell proliferation, increase NK cell lytic potential and modulate MHC expression.

Question 08

IgG in neonatal blood is mostly maternal in origin.
True
False
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Explanation

The newborn infant relies on maternal passage of IgG until about 6 months of age when the infant produces its own IgG

Question 09

In general, infants respond less well to immunisations than older children and adults.
True
False
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Explanation

The timing of the immunisation schedule needs to balance the risk of disease the longer an immunisation is delayed with the decreased effectiveness of an immunisation the earlier it is given.

Question 10

A woman at 30 weeks gestation with florid rubella infection can be reassured about the lack of adverse effect of the virus on the fetus.
True
False
Check answer

Explanation

The risk of Congenital Rubella Syndrome are largely in the first trimester, and after 20 weeks gestation the risks of significant problems in the fetus are minimal.

Question 11

Because of the dangers of rubella infection in pregnancy, pregnant women who are not immune to rubella should be immunised.
True
False
Check answer

Explanation

Rubella immunisation cannot be given to pregnant women. See Immunisation handbook 'MMR and monovalent rubella vaccines should not be given to a woman known to be pregnant, and pregnancy should be avoided for 28 days after vaccination.'

Question 12

Diphtheria vaccine does not prevent infection with the causative organism (Corynebacterium diphtheriae).
True
False
Check answer

Explanation

Diphtheria vaccination stimulates the production of antitoxin, which protects against the toxin produced by the organism.
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