Question 01: In classical PKU: |
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Phenylalanine dehydrogenase is deficient |
The biochemical deficiency in PKU interferes with the conversion of phenylalanine to tyrosine |
The co-factor tetrahydrobiopterin is deficient |
Phenylalanine hydroxylase is not deficient |
Check answer |
ExplanationThe enzyme phenylalanine hydroxylase, which converts phenylalanine to tyrosine is deficient in classical PKU. The co-factor tetrahydrobiopterin is not deficient in classical PKU. There is no enzyme called phenylalanine dehydrogenase. |